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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PlGF-1 Antibody   

PlGF-1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49763
Other Accession AAD30179
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 24789 Da
Additional Information
Gene ID 5228
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human PIGF can be used as a positive control.
Other Names PIGF1, PIGF 1, PIGF-1, Phosphatidylinositol glycan biosynthesis class F, PIG F
Target/Specificity PIGF
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human PlGF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPlGF-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGF
Synonyms PGFL, PLGF
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Cellular Location Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
Tissue Location While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas
Research Areas
Citations (0)

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PlGF-1(also called Placenta Growth Factor-1, PLGF, and PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals thro µgh the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.

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$ 265.00
$ 89.00
Cat# ABV11057
(40 western blots)
Availability: 5-7days
Bulk Size
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