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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TFF-2/Spasmolysin Antibody   

TFF-2/Spasmolysin Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03403
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 14284 Da
Additional Information
Gene ID 7032
Application & Usage Western blot analysis (0.5-2 µg/ml). Per researchers feedback, it can also be used in ELISA (2-3 µg/ml) and neutralization (3-6 µg/ml). However, the optimal conditions should be determined individually.
Other Names TFF-2, TFF 2, TFF2, trefoil factor 2, Spasmolytic polypeptide, SP, Spasmolysin
Target/Specificity TFF-2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-human TFF-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTFF-2/Spasmolysin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFF2
Synonyms SML1
Function Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
Cellular Location Secreted.
Tissue Location Stomach.
Research Areas
Citations (0)

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The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data s µggests a potential role for TFF2 in acute and chronic asthma. Human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues.

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$ 245.00
$ 89.00
Cat# ABV11059
(40 western blots)
Availability: 5-7days
Bulk Size
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