|Calculated MW||45055 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). Recombinant human GDF-9 can be used as a positive control. However, the optimal concentrations should be determined individually.|
|Other Names||GDF9, GDF 9, GDF-9, Growth differentiation factor 9|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||GDF-9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.|
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Provided below are standard protocols that you may find useful for product applications.
GDF-9 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-3. Unlike most TGF-family members, GDF-9 and GDF-3 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. GDF-9 is expressed in oocytes and is required for normal ovarian folliculogenesis. Human GDF-9 is a 31.0 kDa non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains.
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