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Superoxide Dismutase 4 (SOD-4) Antibody (3A1)

Mouse Monoclonal Antibody

  • WB - Superoxide Dismutase 4 (SOD-4) Antibody (3A1) ABV11164
    WB analysis of cell lysates. Lane 1: HeLa cells, Lane 2: Jurkat cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14618
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG 2a
Clone Names 3A1
Calculated MW 29041 Da
Additional Information
Gene ID 9973
Positive Control WB analysis of HeLa and Jurkat cell lysates. IHC analysis : normal human lymphoid tissue, normal human tonsillar tissue
Application & Usage Western blot: 1:2000, IP: 2 µl, IHC-P, ELISA.
Other Names Superoxide dismutase, SOD4.
Target/Specificity SOD4
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSuperoxide Dismutase 4 (SOD-4) Antibody (3A1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCS
Function Delivers copper to copper zinc superoxide dismutase (SOD1).
Cellular Location Cytoplasm.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. SOD4 delivers copper to copper zinc superoxide dismutase (SOD1).

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$ 325.00
Cat# ABV11164
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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