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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Glutathione Peroxidase 3 Antibody (Clone 55A)   

Glutathione Peroxidase 3 Antibody (Clone 55A)

Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22352
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG2b
Clone Names Clone 55A
Calculated MW 25552 Da
Additional Information
Gene ID 2878
Positive Control WB and IP:Bosc23 cell lysate
Application & Usage IP: 1-2 µl, ELISA.
Other Names GPX3
Target/Specificity Glutathione Peroxidase 3
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGlutathione Peroxidase 3 Antibody (Clone 55A) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPX3
Synonyms GPXP
Function Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
Cellular Location Secreted.
Tissue Location Secreted in plasma.
Research Areas
Citations (0)

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Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

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$ 325.00
Cat# ABV11177
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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