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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   ACE Antibody (CT)   

ACE Antibody (CT)

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12821
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 149715 Da
Additional Information
Gene ID 1636
Positive Control Western blot: mouse liung tissue lysate
Application & Usage Western blot: 1:1000
Other Names ACE; DCP; DCP1; Angiotensin-converting enzyme; Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen - CD143; Angiotensin-converting enzyme, soluble form
Target/Specificity ACE
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsACE Antibody (CT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACE
Synonyms DCP, DCP1
Function Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Cellular Location Angiotensin-converting enzyme, soluble form: Secreted
Tissue Location Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis
Research Areas
Citations (0)

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Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exo-peptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis. Although it bears significant sequence homology to ACE, ACE2 shows a more restricted pattern of expression. ACE is expressed ubiquitously throughout the vasculature while ACE2 is expressed only in cardiac, renal and testicular cells.

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$ 245.00
Cat# ABV11253
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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