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HMG2L1 polyclonal antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UGU5
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 65712 Da
Additional Information
Gene ID 10042
Positive Control ELISA: Peptides.
Application & Usage ELISA: 1:1000.
Other Names HMGXB4
Target/Specificity HMG2L1
Antibody Form Liquid
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHMG2L1 polyclonal antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HMG2L1, HMGBCG
Function Negatively regulates Wnt/beta-catenin signaling during development.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}
Citations (0)

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High mobility group (HMG) protein 1 and 2 has been classified by DNA binding preferences and are ubiquitous non-histone components of chromatin. They bind to the minor groove of AT-rich DNA sequences with high affinity. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFkB family, ATF-2 and c-Jun to activate transcription. HMG-2L1 (High mobility group protein 2-like 1), also known as HMGBCG, is a member of the HMG chromosomal protein superfamily. It contains a single HMG box DNA binding domain, and therefore does not contain an acidic C-terminal tail. HMG-2L1 is expressed in the nucleus and may play a role in transcriptional regulation.

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$ 185.00
Cat# ABV11396
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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