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CD58 Antibody

Rabbit Polyclonal Antibody

  • WB - CD58 Antibody ABV11450
    Western blot analysis of CD58 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19256
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 28147 Da
Additional Information
Gene ID 965
Positive Control WB: HEK293T, Raw264.7, H9C2 whole cell lysates
Application & Usage WB: 1:500 - 1:1000
Other Names LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58
Target/Specificity CD58
Antibody Form Liquid
Appearance Colorless liquid
Formulation 1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCD58 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD58
Synonyms LFA3
Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell surface.

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$ 190.00
Cat# ABV11450
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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