ACAD-9 Antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | B1WC61 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 68843 Da |
Gene ID | 294973 |
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Other Names | ACAD9 protein |
Target/Specificity | ACAD-9 |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-ACAD-9 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Background Descriptions | |
Precautions | ACAD-9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Acad9 {ECO:0000312|RGD:727973} |
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Function | As part of the MCIA complex, primarily participates in the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphorylation. This moonlighting protein has also a dehydrogenase activity toward a broad range of substrates with greater specificity for long-chain unsaturated acyl-CoAs. However, in vivo, it does not seem to play a primary role in fatty acid oxidation. In addition, the function in complex I assembly is independent of the dehydrogenase activity of the protein. |
Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9H845}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H845}; Matrix side {ECO:0000250|UniProtKB:Q9H845}. Note=Essentially associated with membranes. {ECO:0000250|UniProtKB:Q9H845} |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACAD-9 is a member of the acyl-CoA dehydrogenase family (ACAD). ACAD-9 is localized to the mitochondria and plays a key role in the β-oxidation of long-chain unsaturated fatty acids. ACAD-9 is active toward palmitoyl-CoA and stearoyl-CoA substrates.
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