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MCP-1 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - MCP-1 Antibody ABV11578
    Western blot analysis of MCP-1 in LPS treated RAW cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, Neut
Primary Accession P14844
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 16460 Da
Additional Information
Gene ID 24770
Other Names MCP1, MCP-1, MCP 1, monocyte chemoattracctant protein-1, monocyte chemoattracctant protein 1, monocyte chemoattracctant protein
Target/Specificity MCP-1/MCAF
Format 100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-rat MCP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsMCP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ccl2
Synonyms Je, Mcp1, Scya2
Function Chemotactic factor that attracts monocytes, but not neutrophils.
Cellular Location Secreted.
Research Areas
Citations (0)

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Rat MCP-1/JE (monocyte chemoattractant protein-1) is a 148-amino acid CC chemokine with a N-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con-A-stimulated rat spleen cDNA library. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3’-end. The 3’-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and which explains for the higher molecular weight (25 kDa). In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophiles. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli.

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$ 265.00
Cat# ABV11578
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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