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N6-Methyladenosine Antibody

Purified Rabbit Polyclonal Antibody

  • WB - N6-Methyladenosine Antibody ABV11630
    Western blot analysis by Anti-N6-MA. Lane1: N6-Methyladenosine conjugated with BSA (2ng); Lane2: Adenosine conjugated with BSA (2ng).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Mammalian
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Additional Information
Other Names m6A
Target/Specificity N6-Methyl Adenosine
Format 100 µg (1 mg/ml) in PBS (prepared using DEPC-treated water) with 0.09% (W/V) sodium azide.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsN6-Methyladenosine Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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N6-methyladenosine (m6A), or methylation of the N6 position of adenosine is a posttranscriptional modification of RNA. Due to a lack of analytical methods, N6-methyladenosine is poorly understood, but new evidence suggests that it is a very common base modification and important physiological regulator. N6-methyladenosine is markedly increased throughout brain development, and is enriched near stop codons, microRNA-binding sites and UTRs, which indicates a fundamental role in the regulation of gene expression. N6-methyladenosine is also highly conserved between human and mouse. The regulation of m6A modifications in mRNA has been linked to disease, where fat mass and obesity-associated (FTO) has been has been reported to be a obesity risk gene. FTO is a m6A demethylase and polymorphisms that result in increased FTO expression are associated with increased body mass and risk of obesity.

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$ 275.00
$ 89.00
Cat# ABV11630
(40 western blots)
Availability: 5-7days
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