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CIDE-C Antibody

Purified Rabbit Polyclonal Antibody

  • WB - CIDE-C Antibody ABV11642
    CIDEC Antibody western blot analysis in MDA-MA453 cell line lysates(35ug/lane). This demonstrates the CIDEC antibody detected the CIDEC protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A9Q0Q7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional Information
Other Names Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC, FSP27
Target/Specificity CIDE-C
Format In PBS with 0.09% (W/V) sodium azide
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsCIDE-C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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CIDEC binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression

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$ 265.00
Cat# ABV11642
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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