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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD27 Polyclonal Antibody    

CD27 Polyclonal Antibody

Rabbit Anti Human Polyclonal Antibody

  • FC - CD27 Polyclonal Antibody  ABV11720
    Flow cytometric analysis of ramos cells(right) compared to a negative control cell(left).
  • WB - CD27 Polyclonal Antibody  ABV11720
    1: Ramos; 2: 293 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26842
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 29137 Da
Additional Information
Gene ID 939
Positive Control FC
Application & Usage WB~~1:1000 FC~~1:10~50
Other Names CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Target/Specificity CD27
Antibody Form Liquid
Appearance Colorless liquid
Formulation PBS with 0.09% (W/V) sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCD27 Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD27
Synonyms TNFRSF7
Function Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Found in most T-lymphocytes.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

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$ 155.00
Cat# ABV11720
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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