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CD44 Monoclonal Antibody

Mouse Anti Human Monoclonal Antibody

  • FC - CD44 Monoclonal Antibody ABV11724
    Flow cytometric analysis of Hela cells (right) compared to a negative control cell (left) using CD44 antibody.
  • IF - CD44 Monoclonal Antibody ABV11724
    CD44 antibody confocal immunofluorescent analysis with Hela cell.
  • IHC - CD44 Monoclonal Antibody ABV11724
    CD44 staining in human lung adenocarcinoma tissue sections by immunohistochemistrty.
  • WB - CD44 Monoclonal Antibody ABV11724
    Western blot analysis using CD44 antibody in Lane1: Hela; Lane2: HUVEC whole cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16070
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG2a ,K
Clone Names Hermes-3
Calculated MW 81538 Da
Additional Information
Gene ID 960
Positive Control WB, IHC, IF. FC
Application & Usage IHC-P~~1:10~50, WB~~1:2000, IF~~1:10~50, FC~~1:10~50
Other Names CD44 , homing cell adhesion molecule, cell adhesion molecule, LHR, MDU2, MDU3, MIC4
Target/Specificity CD44
Antibody Form Liquid
Appearance Colorless liquid
Formulation PBS with 0.09% (W/V) sodium azide. 
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCD44 Monoclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD44
Synonyms LHR, MDU2, MDU3, MIC4
Function Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
Tissue Location Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas Expression is repressed in neuroblastoma cells
Research Areas
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The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

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$ 155.00
Cat# ABV11724
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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