Anti-STEAP2 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC |
---|---|
Primary Accession | Q8NFT2 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 56056 Da |
Gene ID | 261729 |
---|---|
Positive Control | WB: HEK293T, mouse spleen, rat spleen cell lysate; IHC: human colon cancer; IFC: HEK293T cells |
Application & Usage | WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100 |
Alias Symbol | STEAP2 |
Other Names | PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1 |
Appearance | Colorless liquid |
Formulation | In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Anti-STEAP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STEAP2 |
---|---|
Synonyms | PCANAP1, STAMP1 |
Function | Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (By similarity). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (By similarity). |
Cellular Location | Endosome membrane {ECO:0000250|UniProtKB:Q8BWB6}; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of the STEAP family. The STEAP proteins are metalloreductases that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor
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