Anti-HAPLN4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q86UW8 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Isotype | Rabbit IgG |
Calculated MW | 42801 Da |
Gene ID | 404037 |
---|---|
Positive Control | WB: THP1, mouse spleen, rat spleen cell lysates. |
Application & Usage | WB; 1:500 – 1:2000 |
Other Names | BRAL2; KIAA1926; Hyaluronan and proteoglycan link protein 4; Brain link protein 2 |
Target/Specificity | HAPLN4 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Handling | The antibody solution should be gently mixed before use |
Reconstitution & Storage | -20°C |
Background Descriptions | |
Precautions | Anti-HAPLN4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HAPLN4 |
---|---|
Synonyms | BRAL2, KIAA1926 |
Function | Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (By similarity). Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons (By similarity). |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9ESM3} |
Tissue Location | Expressed predominantly in brain. |
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