|Reactivity||Human, Mouse, Rat|
|Calculated MW||22969 Da|
|Positive Control||WB: Jurkat, A549, MCF7, mouse lung, rat lung lysate|
|Application & Usage||WB; 1:500 – 1:2000, IF/IC; 1:50 – 1:100|
|Other Names||Histone chaperone ASF1A, Anti-silencing function protein 1 homolog A, hAsf1, hAsf1a, CCG1-interacting factor A, CIA, hCIA|
|Handling||The antibody solution should be gently mixed before use|
|Reconstitution & Storage||-20°C|
|Precautions||Anti-ASF1A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.|
|Tissue Location||Ubiquitously expressed.|
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