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58K Golgi protein(N-Term)/FTCD AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1003a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
58K Golgi protein(N-Term)/FTCD Antibody - Product info | |
| Other Accession | NP_996848 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
58K Golgi protein(N-Term)/FTCD Antibody - Additional info | |
| Other Names FTCD; LCHC1; formiminotransferase cyclodeaminase; formimidoyltransferase cyclodeaminase | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions 58K Golgi protein(N-Term)/FTCD Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
58K Golgi protein(N-Term)/FTCD Antibody - Application data
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AF1003a (0.03 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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AF1003a (3.8 µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
58K Golgi protein(N-Term)/FTCD Antibody - Related products
AP6646b: FTCD Antibody (C-term)
AP6646c: FTCD Antibody (Center)
BP6646b: FTCD Antibody (C-term) Blocking Peptide
BP6646c: FTCD Antibody (Center) Blocking Peptide
AT2112a: FTCD Antibody (monoclonal) (M01)
AT2113a: FTCD Antibody (monoclonal) (M02)
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BACKGROUND
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
REFERENCES
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Chapuis J, et al. Mol Psychiatry, 2009 Nov. PMID 19204726. An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). Franke B, et al. Birth Defects Res A Clin Mol Teratol, 2009 Mar. PMID 19161160.
