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ABCB9 / TAPL AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1008a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ABCB9 / TAPL Antibody - Product info | |
| Other Accession | NP_982269 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
ABCB9 / TAPL Antibody - Additional info | |
| Other Names ABCB9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; TAPL; KIAA1520; EST122234 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCB9 / TAPL Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCB9 / TAPL Antibody - Application data
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AF1008a (3.8 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
ABCB9 / TAPL Antibody - Related products
AP6115a: ABCB9 Antibody (C-term)
RI10019: ABCB9 predesign siRNA
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.
REFERENCES
Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain. Demirel O, et al. Traffic, 2010 Mar. PMID 20377823. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046. Functional dissection of transmembrane domains of human TAP-like (ABCB9). Kamakura A, et al. Biochem Biophys Res Commun, 2008 Dec 19. PMID 18952056. Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL). Zhao C, et al. J Biol Chem, 2008 Jun 20. PMID 18434309. Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells. Ohara T, et al. Biol Pharm Bull, 2008 Jan. PMID 18175933.
