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Goat Anti-AGR2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-AGR2 Antibody AF1035a
    AF1035a (0.01 µg/ml) staining of Human Duodenum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95994
Other Accession NP_006399, 10551, 23795 (mouse)
Reactivity Human
Predicted Mouse, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 19979 Da
Additional Information
Gene ID 10551
Other Names Anterior gradient protein 2 homolog, AG-2, hAG-2, HPC8, Secreted cement gland protein XAG-2 homolog, AGR2, AG2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-AGR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGR2
Synonyms AG2
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Cellular Location Secreted. Endoplasmic reticulum
Tissue Location Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.
Research Areas
Citations (0)

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Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia. Chen R, et al. Mol Cancer, 2010 Jun 15. PMID 20550709.
Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Lipkin SM, et al. Cancer Prev Res (Phila), 2010 May. PMID 20403997.
ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer. Zhang Y, et al. Cancer Res, 2010 Jan 1. PMID 20048076.
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients. Barraclough DL, et al. Am J Pathol, 2009 Nov. PMID 19834055.
Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma. Riener MO, et al. Histol Histopathol, 2009 Sep. PMID 19609859.

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$ 325.00
Cat# AF1035a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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