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Goat Anti-AGTR1 / AT1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-AGTR1 / AT1 Antibody AF1036a
    AF1036a (0.3 µg/ml) staining of Mouse Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30556
Other Accession NP_114438, 185, 11607 (mouse), 24180 (rat)
Reactivity Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 41061 Da
Additional Information
Gene ID 185
Other Names Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor, AT1, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-AGTR1 / AT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGTR1
Synonyms AGTR1A, AGTR1B, AT2R1, AT2R1B
Function Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Liver, lung, adrenal and adrenocortical adenomas
Research Areas
Citations (0)

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Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.


Renin angiotensin system polymorphisms in patients with metabolic syndrome (MetS). Procopciuc LM, et al. Eur J Intern Med, 2010 Oct. PMID 20816596.
A1166C genetic variation of the angiotensin II type I receptor gene and susceptibility to coronary heart disease: Collaborative of 53 studies with 20,435 cases and 23,674 controls. Xu M, et al. Atherosclerosis, 2010 Aug 4. PMID 20732682.
Association of the angiotensin II type I receptor gene +1166 A>C polymorphism with hypertension risk: evidence from a meta-analysis of 16474 subjects. Niu W, et al. Hypertens Res, 2010 Aug 12. PMID 20703234.
A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.
Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population. Schuur M, et al. J Neurol Neurosurg Psychiatry, 2010 Jul 28. PMID 20667857.

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$ 325.00
Cat# AF1036a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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