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AKT3 AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1049a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AKT3 Antibody - Product info | |
| Other Accession | NP_859029 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
AKT3 Antibody - Additional info | |
| Other Names AKT3; PKBG; PRKBG; STK-2; RAC-gamma; RAC-PK-gamma; DKFZP434N0250; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); protein kinase B gamma; serine threonine protein kinase, Akt-3; RAC-gamma serine/threonine protein kinase; PKB-GAMMA; AKT3 kinase; OTTHUMP00000037911; OTTHUMP00000037912 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AKT3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
AKT3 Antibody - Application data
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AF1049a (1 µg/ml) staining of HepG2lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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HEK293 overexpressing AKT3 (RC224750) and probed with AF1049a (mock transfection in second lane), tested by Origene.
AKT3 Antibody - Related products
AM1849a: AKT3 Antibody (Ascites)
AP3468a: Phospho-AKT3-S472 Antibody
AP7030a: AKT3 Antibody (N-term)
AP7030c: AKT3 Antibody (Center)
AP8647b: AIK3 Antibody (C-term)
BP3468a: Phospho-AKT3-S472 Antibody Blocking Peptide
BP7030c: AKT3 Antibody (Center) Blocking Peptide
BP7030d: AKT3 Antibody (S472) Blocking Peptide
BP7030e: AKT3 Antibody (T447) Blocking Peptide
BP8647b: AIK3 Antibody (C-term) Blocking Peptide
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BACKGROUND
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts. Wickenden JA, et al. Breast Cancer Res, 2010. PMID 20398329. Energy balance, the PI3K-AKT-mTOR pathway genes, and the risk of bladder cancer. Lin J, et al. Cancer Prev Res (Phila), 2010 Apr. PMID 20354165. Mutational and immunohistochemical study of the PI3K/Akt pathway in papillary thyroid carcinoma in Greece. Sozopoulos E, et al. Endocr Pathol, 2010 Jun. PMID 20186503. Akt2 and Akt3 play a pivotal role in malignant gliomas. Mure H, et al. Neuro Oncol, 2010 Mar. PMID 20167810.
