|Application ||WB, IHC, E|
|Other Accession||NP_001968, 2028, 13809 (mouse)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||109244 Da|
|Other Names||Glutamyl aminopeptidase, EAP, 188.8.131.52, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Aminopeptidase A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. Kalsi G, et al. Hum Mol Genet, 2010 Jun 15. PMID 20332099.
Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma. P茅rez I, et al. Head Neck, 2009 Oct. PMID 19373777.
Aminopeptidase A contributes to the N-terminal truncation of amyloid beta-peptide. Sevalle J, et al. J Neurochem, 2009 Apr. PMID 19187443.
Evaluation of role of angiotensin III and aminopeptidases in prostate cancer cells. Teranishi J, et al. Prostate, 2008 Nov 1. PMID 18677709.
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