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Goat Anti-Aminopeptidase A Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-Aminopeptidase A Antibody AF1058a
    AF1058a staining (1 µg/ml) of Human Testis lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
    detail
  • IHC - Goat Anti-Aminopeptidase A Antibody AF1058a
    AF1058a (3.8 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q07075
Other Accession NP_001968, 2028, 13809 (mouse)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 109244 Da
Additional Information
Gene ID 2028
Other Names Glutamyl aminopeptidase, EAP, 3.4.11.7, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Aminopeptidase A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENPEP
Function Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
Research Areas
Citations (0)
citation

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References

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. Kalsi G, et al. Hum Mol Genet, 2010 Jun 15. PMID 20332099.
Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma. P茅rez I, et al. Head Neck, 2009 Oct. PMID 19373777.
Aminopeptidase A contributes to the N-terminal truncation of amyloid beta-peptide. Sevalle J, et al. J Neurochem, 2009 Apr. PMID 19187443.
Evaluation of role of angiotensin III and aminopeptidases in prostate cancer cells. Teranishi J, et al. Prostate, 2008 Nov 1. PMID 18677709.

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$ 341.00
Cat# AF1058a
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