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Goat Anti-ARPC2 Antibody

Peptide-affinity purified goat antibody

  • IHC - Goat Anti-ARPC2 Antibody AF1109a
    AF1109a (3.8 µg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • WB - Goat Anti-ARPC2 Antibody AF1109a
    AF1109a staining (0.2 µg/ml) of Hela lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15144
Other Accession NP_690601, 10109, 76709 (mouse)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 34333 Da
Additional Information
Gene ID 10109
Other Names Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC, ARPC2, ARC34
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ARPC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARPC2
Synonyms ARC34
Function Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Cellular Location Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome
Research Areas
Citations (0)

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This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.


Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin. Monfregola J, et al. J Biol Chem, 2010 May 28. PMID 20308062.
Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk. Festen EA, et al. Am J Gastroenterol, 2010 Feb. PMID 19861958.
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Franke A, et al. Nat Genet, 2008 Nov. PMID 18836448.
Overexpression of N-WASP in the brain of human epilepsy. Xiao F, et al. Brain Res, 2008 Oct 3. PMID 18708039.
Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.

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$ 325.00
Cat# AF1109a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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