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BAF53A and BAF53B AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1136a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
BAF53A and BAF53B Antibody - Product info | |
| Application | WB
|
| Other Accession | NP_057272 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
BAF53A and BAF53B Antibody - Additional info | |
| Other Names BAF53A; BAF53B; ACTL6; BAF53a; BAF53b; actin-like 6A; actin-like 6B; hArpN alpha; actin-related protein; ACTL6A; ACTL6B; 53 kDa BRG1-associated factor B; ARPN-BETA; MGC5382 Arp4; INO80K; BAF complex 53 kDa subunit; BAF53; BRG1-associated factor; INO80 complex subunit K; actin-related protein 4; hArpN beta | |
| Dilution WB~~1:200~500 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BAF53A and BAF53B Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
BAF53A and BAF53B Antibody - Application data
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AF1136a staining (1 µg/ml) of Hela lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
BAF53A and BAF53B Antibody - Related products
AP5327a: ACTL6B Antibody (N-term)
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BACKGROUND
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
REFERENCES
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo C, et al. Mol Cell, 2007 Jul 20. PMID 17643375. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Doyon Y, et al. Mol Cell, 2006 Jan 6. PMID 16387653. Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514. A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
