|Application ||WB, IHC, E|
|Other Accession||NP_660339, 199731, 260299 (mouse)|
|Calculated MW||42785 Da|
|Other Names||Cell adhesion molecule 4, Immunoglobulin superfamily member 4C, IgSF4C, Nectin-like protein 4, NECL-4, TSLC1-like protein 2, CADM4, IGSF4C, NECL4, TSLL2|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CADM4 (internal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||IGSF4C, NECL4, TSLL2|
|Function||Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in brain, prostate, brain, kidney and some other organs.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. Karasik D, et al. J Bone Miner Res, 2010 Jul. PMID 20200953.
The cell adhesion nectin-like molecules (Necl) 1 and 4 suppress the growth and tumorigenic ability of colon cancer cells. Raveh S, et al. J Cell Biochem, 2009 Sep 1. PMID 19565570.
A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands. Giallourakis C, et al. Genome Res, 2006 Aug. PMID 16825666.
Cell adhesion and prostate tumor-suppressor activity of TSLL2/IGSF4C, an immunoglobulin superfamily molecule homologous to TSLC1/IGSF4. Williams YN, et al. Oncogene, 2006 Mar 9. PMID 16261159.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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