|Application ||WB, E|
|Other Accession||NP_775545, 74256 (mouse), 312937 (rat)|
|Other Names||CYLD antibody, cylindromatosis (turban tumor syndrome) antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, CDMT antibody, CYLD1 antibody, EAC antibody, mKIAA0849 antibody, ubiquitin carboxyl-terminal hydrolase CYLD antibody|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Cyld (mouse) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Thymocyte-specific truncation of the deubiquitinating domain of CYLD impairs positive selection in a NF-kappaB essential modulator-dependent manner. Tsagaratou A, et al. J Immunol, 2010 Aug 15. PMID 20644164.
Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A. Chang J, et al. Proc Natl Acad Sci U S A, 2010 May 4. PMID 20404153.
CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling. Lee AJ, et al. J Biol Chem, 2010 May 21. PMID 20233721.
Regulation of natural killer T-cell development by deubiquitinase CYLD. Lee AJ, et al. EMBO J, 2010 May 5. PMID 20224552.
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. Wickstr枚m SA, et al. EMBO J, 2010 Jan 6. PMID 19893491.
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