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Goat Anti-Fibroblast growth factor 21 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Fibroblast growth factor 21 Antibody AF1417a
    AF1417a (1 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NSA1
Other Accession NP_061986, 26291
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 22300 Da
Additional Information
Gene ID 26291
Other Names Fibroblast growth factor 21, FGF-21, FGF21
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Fibroblast growth factor 21 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF21
Function Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
Cellular Location Secreted.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.


FGF21 signalling pathway and metabolic traits - genetic association analysis. Kaess BM, et al. Eur J Hum Genet, 2010 Aug 18. PMID 20717167.
Daily physical activity, fasting glucose, uric acid, and body mass index are independent factors associated with serum fibroblast growth factor 21 levels. Cuevas-Ramos D, et al. Eur J Endocrinol, 2010 Sep. PMID 20566587.
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Dushay J, et al. Gastroenterology, 2010 Aug. PMID 20451522.
Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha. Wang Y, et al. J Biol Chem, 2010 May 21. PMID 20332535.
Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa. Fazeli PK, et al. J Clin Endocrinol Metab, 2010 Jan. PMID 19926712.

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$ 325.00
Cat# AF1417a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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