Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Goat Anti-FOXQ1 / FKHRL1 Antibody   

Goat Anti-FOXQ1 / FKHRL1 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-FOXQ1 / FKHRL1 Antibody AF1440a
    AF1440a staining (1 µg/ml) of H460 lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9C009
Other Accession NP_150285, 94234, 15220 (mouse)
Reactivity Human
Predicted Mouse
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Additional Information
Other Names Forkhead box protein Q1, HNF-3/forkhead-like protein 1, HFH-1, Hepatocyte nuclear factor 3 forkhead homolog 1, FOXQ1, HFH1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-FOXQ1 / FKHRL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXQ1
Synonyms HFH1
Function Plays a role in hair follicle differentiation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}
Tissue Location Expressed predominantly in the stomach, trachea, bladder and salivary gland EMBL; AF225950; AAK00639.1; -; Genomic_DNA EMBL; AF153341; AAF75586.1; -; Genomic_DNA EMBL; BC053850; AAH53850.1; -; mRNA CCDS; CCDS4471.1; - RefSeq; NP_150285.3; NM_033260.3 UniGene; Hs.591352; - ProteinModelPortal; Q9C009; - SMR; Q9C009; - BioGrid; 125147; 105 IntAct; Q9C009; 105 MINT; Q9C009; - STRING; 9606.ENSP00000296839; - iPTMnet; Q9C009; - PhosphoSitePlus; Q9C009; - BioMuta; FOXQ1; - DMDM; 143811391; - EPD; Q9C009; - MaxQB; Q9C009; - PaxDb; Q9C009; - PeptideAtlas; Q9C009; - PRIDE; Q9C009; - ProteomicsDB; 79939; - Ensembl; ENST00000296839; ENSP00000296839; ENSG00000164379 GeneID; 94234; - KEGG; hsa:94234; - UCSC; uc003mtl.5; human CTD; 94234; - DisGeNET; 94234; - EuPathDB; HostDB:ENSG00000164379.5; - GeneCards; FOXQ1; - H-InvDB; HIX0025221; - HGNC; HGNC:20951; FOXQ1 HPA; HPA059700; - MIM; 612788; gene neXtProt; NX_Q9C009; - OpenTargets; ENSG00000164379; - PharmGKB; PA134924898; - eggNOG; KOG2294; Eukaryota eggNOG; COG5025; LUCA GeneTree; ENSGT00920000148947; - HOGENOM; HOG000112634; - HOVERGEN; HBG051658; - InParanoid; Q9C009; - KO; K09410; - OMA; AYGMGEP; - OrthoDB; EOG091G0LMU; - PhylomeDB; Q9C009; - TreeFam; TF316127; - SignaLink; Q9C009; - ChiTaRS; FOXQ1; human GenomeRNAi; 94234; - PRO; PR:Q9C009; - Proteomes; UP000005640; Chromosome 6 Bgee; ENSG00000164379; - CleanEx; HS_FOXQ1; - Genevisible; Q9C009; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001078; F:transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central GO; GO:0030154; P:cell differentiation; IBA:GO_Central GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW CDD; cd00059; FH; 1 Gene3D; 1.10.10.10; -; 1 InterPro; IPR001766; Fork_head_dom InterPro; IPR018122; TF_fork_head_CS_1 InterPro; IPR030456; TF_fork_head_CS_2 InterPro; IPR036388; WH-like_DNA-bd_sf InterPro; IPR036390; WH_DNA-bd_sf Pfam; PF00250; Forkhead; 1 PRINTS; PR00053; FORKHEAD SMART; SM00339; FH; 1 SUPFAM; SSF46785; SSF46785; 1 PROSITE; PS00657; FORK_HEAD_1; 1 PROSITE; PS00658; FORK_HEAD_2; 1 PROSITE; PS50039; FORK_HEAD_3; 1 2: Evidence at transcript level; Complete proteome; DNA-binding; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 403 Forkhead box protein Q1 /FTId=PRO_0000091890 DNA_BIND 119 214 Fork-head. {ECO:0000255|PROSITE- ProRule:PRU00089} COMPBIAS 13 103 Ala/Gly-rich COMPBIAS 221 397 Pro-rich VARIANT 60 60 T -> P (in dbSNP:rs9502889) /FTId=VAR_031606 VARIANT 61 61 Q -> P (in dbSNP:rs9502890) /FTId=VAR_031607 CONFLICT 49 52 NSPA -> KPS (in Ref. 2; AAF75586) CONFLICT 386 386 S -> L (in Ref. 2; AAF75586) CONFLICT 395 395 P -> S (in Ref. 2; AAF75586) SEQUENCE 403 AA; 41526 MW; 0709E0A6A0AE2174 CRC64; MKLEVFVPRA AHGDKQGSDL EGAGGSDAPS PLSAAGDDSL GSDGDCAANS PAAGGGARDT QGDGEQSAGG GPGAEEAIPA AAAAAVVAEG AEAGAAGPGA GGAGSGEGAR SKPYTRRPKP PYSYIALIAM AIRDSAGGRL TLAEINEYLM GKFPFFRGSY TGWRNSVRHN LSLNDCFVKV LRDPSRPWGK DNYWMLNPNS EYTFADGVFR RRRKRLSHRA PVPAPGLRPE EAPGLPAAPP PAPAAPASPR MRSPARQEER ASPAGKFSSS FAIDSILRKP FRSRRLRDTA PGTTLQWGAA PCPPLPAFPA LLPAAPCRAL LPLCAYGAGE PARLGAREAE VPPTAPPLLL APLPAAAPAK PLRGPAAGGA HLYCPLRLPA ALQAASVRRP GPHLPYPVET LLA
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).

References

FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Kaneda H, et al. Cancer Res, 2010 Mar 1. PMID 20145154.
Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients. L茅ger B, et al. Muscle Nerve, 2009 Jul. PMID 19533653.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor. Samatar AA, et al. J Biol Chem, 2002 Aug 2. PMID 12011061.

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 335.00
Cat# AF1440a
Size:
Quantity:
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions