|Application ||WB, E|
|Other Accession||NP_861455, 350383|
|Calculated MW||51106 Da|
|Other Names||Probable G-protein coupled receptor 142, G-protein coupled receptor PGR2, GPR142, PGR2|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-GPR142 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Exclusively expressed in the central nervous system, most abundantly in the ventrolateral region of caudate putamen, the habenular nucleus, the zona incerta, and the medial mammillary nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).
Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system. Matsuo A, et al. Biochem Biophys Res Commun, 2005 May 27. PMID 15845401.
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. Fredriksson R, et al. FEBS Lett, 2003 Nov 20. PMID 14623098.
The G protein-coupled receptor repertoires of human and mouse. Vassilatis DK, et al. Proc Natl Acad Sci U S A, 2003 Apr 15. PMID 12679517.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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