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Goat Anti-HMGB3 / HMG4 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-HMGB3 / HMG4 Antibody AF1533a
    AF1533a (0.01 µg/ml) staining of Human Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15347
Other Accession NP_005333, 3149, 15354 (mouse)
Reactivity Human
Predicted Mouse, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 22980 Da
Additional Information
Gene ID 3149
Other Names High mobility group protein B3, High mobility group protein 2a, HMG-2a, High mobility group protein 4, HMG-4, HMGB3, HMG2A, HMG4
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-HMGB3 / HMG4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGB3
Synonyms HMG2A, HMG4
Function Binds preferentially single-stranded DNA and unwinds double-stranded DNA.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}. Chromosome
Tissue Location Expressed predominantly in placenta.
Research Areas
Citations (0)

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HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).


Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation. Nemeth MJ, et al. Proc Natl Acad Sci U S A, 2006 Sep 12. PMID 16945912.
The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901.
The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651.
From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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$ 325.00
Cat# AF1533a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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