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Goat Anti-Neurturin Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Neurturin Antibody AF1728b
    AF1728b (0.1 µg/ml) staining of Human Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99748
Other Accession NP_004549, 4902
Reactivity Human, Mouse
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 22405 Da
Additional Information
Gene ID 4902
Other Names Neurturin, NRTN
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Neurturin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Cellular Location Secreted.
Research Areas
Citations (0)

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Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.


Polymorphisms in the genes encoding the 4 RET ligands, GDNF, NTN, ARTN, PSPN, and susceptibility to Hirschsprung disease. Fernandez RM, et al. J Pediatr Surg, 2008 Nov. PMID 18970938.
Expression patterns of the glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRalpha-1, GFRalpha-2, and a common signal transduction element c-Ret in the human skin hair follicles. Adly MA, et al. J Am Acad Dermatol, 2008 Feb. PMID 18222320.
Glial cell line-derived neurotrophic factor and neurturin inhibit neurite outgrowth and activate RhoA through GFR alpha 2b, an alternatively spliced isoform of GFR alpha 2. Yoong LF, et al. J Neurosci, 2007 May 23. PMID 17522305.
Glial cell-line derived neurotrophic factor and neurturin regulate the expressions of distinct miRNA precursors through the activation of GFRalpha2. Yoong LF, et al. J Neurochem, 2006 Aug. PMID 16895582.
Expression and function of glial cell line-derived neurotrophic factor family ligands and their receptors on human immune cells. Vargas-Leal V, et al. J Immunol, 2005 Aug 15. PMID 16081799.

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$ 325.00
Cat# AF1728b
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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