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Goat Anti-Parvalbumin Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-Parvalbumin Antibody AF1789a
    AF1789a (0.1 µg/ml) staining of Human Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - Goat Anti-Parvalbumin Antibody AF1789a
    AF1789a (0.15 µg/ml) staining of adenovirus-mediated gene transfer in rat heart cells 1) Untransfected, 2) transient transfection with Human PVALB. 3) Untransfected rat skeletal muscle. Primary incubation was 1 hour. Detected by chemiluminescence.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P20472
Other Accession NP_002845, 5816
Reactivity Human, Rat
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 12059 Da
Additional Information
Gene ID 5816
Other Names Parvalbumin alpha, PVALB
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Parvalbumin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PVALB
Function In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation.

References

Parvalbumin: Targeting calcium handling in cardiac diastolic dysfunction. Wang W, et al. Gen Physiol Biophys, 2009. PMID 20093724.
Evaluating PVALB as a candidate gene for SLC12A3-negative cases of Gitelman's syndrome. Riveira-Munoz E, et al. Nephrol Dial Transplant, 2008 Oct. PMID 18469313.
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue. Clements RJ, et al. Exp Brain Res, 2008 May. PMID 18297277.
Quantitative analysis of parvalbumin-immunoreactive cells in the human epileptic hippocampus. Andrioli A, et al. Neuroscience, 2007 Oct 12. PMID 17850980.
Strongly reduced number of parvalbumin-immunoreactive projection neurons in the mammillary bodies in schizophrenia: further evidence for limbic neuropathology. Bernstein HG, et al. Ann N Y Acad Sci, 2007 Jan. PMID 17405923.

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$ 335.00
Cat# AF1789a
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