|Application ||WB, E|
|Other Accession||NP_002845, 5816|
|Calculated MW||12059 Da|
|Other Names||Parvalbumin alpha, PVALB|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Parvalbumin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation.
Parvalbumin: Targeting calcium handling in cardiac diastolic dysfunction. Wang W, et al. Gen Physiol Biophys, 2009. PMID 20093724.
Evaluating PVALB as a candidate gene for SLC12A3-negative cases of Gitelman's syndrome. Riveira-Munoz E, et al. Nephrol Dial Transplant, 2008 Oct. PMID 18469313.
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue. Clements RJ, et al. Exp Brain Res, 2008 May. PMID 18297277.
Quantitative analysis of parvalbumin-immunoreactive cells in the human epileptic hippocampus. Andrioli A, et al. Neuroscience, 2007 Oct 12. PMID 17850980.
Strongly reduced number of parvalbumin-immunoreactive projection neurons in the mammillary bodies in schizophrenia: further evidence for limbic neuropathology. Bernstein HG, et al. Ann N Y Acad Sci, 2007 Jan. PMID 17405923.
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