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Goat Anti-Parvalbumin Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P20472 |
| Other Accession | NP_002845, 5816 |
| Reactivity | Human, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 12059 Da |
| Gene ID | 5816 |
|---|---|
| Other Names | Parvalbumin alpha, PVALB |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-Parvalbumin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PVALB |
|---|---|
| Function | In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation.
References
Parvalbumin: Targeting calcium handling in cardiac diastolic dysfunction. Wang W, et al. Gen Physiol Biophys, 2009. PMID 20093724.
Evaluating PVALB as a candidate gene for SLC12A3-negative cases of Gitelman's syndrome. Riveira-Munoz E, et al. Nephrol Dial Transplant, 2008 Oct. PMID 18469313.
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue. Clements RJ, et al. Exp Brain Res, 2008 May. PMID 18297277.
Quantitative analysis of parvalbumin-immunoreactive cells in the human epileptic hippocampus. Andrioli A, et al. Neuroscience, 2007 Oct 12. PMID 17850980.
Strongly reduced number of parvalbumin-immunoreactive projection neurons in the mammillary bodies in schizophrenia: further evidence for limbic neuropathology. Bernstein HG, et al. Ann N Y Acad Sci, 2007 Jan. PMID 17405923.
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