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Goat Anti-PDCD1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-PDCD1 Antibody AF1800a
    AF1800a (2 µg/ml) staining of Bone marrow lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15116
Other Accession NP_005009, 5133
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 31647 Da
Additional Information
Gene ID 5133
Other Names Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-PDCD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCD1
Synonyms PD1
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.


Association Between Hepatitis B Viral Burden in Chronic Infection and a Functional Single Nucleotide Polymorphism of the PDCD1 Gene. Zheng L, et al. J Clin Immunol, 2010 Aug 11. PMID 20700634.
[Study on the relationship of the haplotypes of programmed cell death 1 gene and ultraviolet history with systemic lupus erythematosus.] Peng C, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2010 Aug. PMID 20677149.
[Programmed cell death 1 (PDCD1) gene polymorphisms and type 1 diabetes in Chilean children] Flores S, et al. Rev Med Chil, 2010 May. PMID 20668808.
Role played by the programmed death-1-programmed death ligand pathway during innate immunity against Mycobacterium tuberculosis. Alvarez IB, et al. J Infect Dis, 2010 Aug 15. PMID 20617899.
PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients. Fichna M, et al. Int J Immunogenet, 2010 Jun 1. PMID 20518841.

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$ 325.00
Cat# AF1800a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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