Goat Anti-PERP Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96FX8 |
Other Accession | NP_071404, 64065, 64058 (mouse), 292949 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 21386 Da |
Gene ID | 64065 |
---|---|
Other Names | p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-PERP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PERP |
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Function | Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. |
Cellular Location | Cell junction, desmosome {ECO:0000250|UniProtKB:Q9JK95}. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes (By similarity). Colocalizes with KRT14 in the cell membrane (PubMed:31898316). {ECO:0000250|UniProtKB:Q9JK95, ECO:0000269|PubMed:31898316} |
Tissue Location | Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts |
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Provided below are standard protocols that you may find useful for product applications.
References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
A Large-scale genetic association study of esophageal adenocarcinoma risk. Liu CY, et al. Carcinogenesis, 2010 Jul. PMID 20453000.
Single-nucleotide polymorphisms in the p53 pathway genes modify cancer risk in BRCA1 and BRCA2 carriers of Jewish-Ashkenazi descent. Yarden RI, et al. Mol Carcinog, 2010 Jun. PMID 20306497.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis. Beaudry VG, et al. Am J Med Genet A, 2009 Sep. PMID 19353588.
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