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RANBP16 / Exportin 7 AntibodyPeptide-affinity purified goat antibody

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AF1908a 0.1mg 400 ul 7-10 days $ 325.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

RANBP16 / Exportin 7 Antibody - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Other AccessionNP_001093632
ReactivityHuman
Concentration100ug/200ul
IsotypeIgG

RANBP16 / Exportin 7 Antibody - Additional info

Other Names
XPO7; Exportin 7; RANBP16; KIAA0745; RAN binding protein 16
Dilution
WB~~1:500~1000
Format
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
RANBP16 / Exportin 7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

RANBP16 / Exportin 7 Antibody - Application data

  • AF1908a staining (0.5 µg/ml) of Hela lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

RANBP16 / Exportin 7 Antibody - Related products

AF1908a: RANBP16 / Exportin 7 Antibody

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.

REFERENCES

STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Dorfman J, et al. Mol Biol Cell, 2008 Apr. PMID 18256292. Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931. A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334. Exportin 7 defines a novel general nuclear export pathway. Mingot JM, et al. EMBO J, 2004 Aug 18. PMID 15282546.