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RARA AntibodyPeptide-affinity purified goat antibody
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AF1913a | 0.1mg 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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RARA Antibody - Product info | |
| Application | WB
|
| Other Accession | NP_001138774 |
| Reactivity | Human |
| Concentration | 100ug/200ul |
| Isotype | IgG |
RARA Antibody - Additional info | |
| Other Names RARA; RAR; NR1B1; retinoic acid receptor, alpha; Retinoic acid receptor, alpha polypeptide; nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form; nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR short form | |
| Dilution WB~~1:2000~17000 | |
| Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RARA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
RARA Antibody - Application data
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AF1913a staining (0.03 µg/ml) of Human Brain lysate (RIPA buffer, 30 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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AF1913a (4 µg/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
RARA Antibody - Related products
LY10628a: RARA Over-expression Lysate
AT3570a: RARA Antibody (monoclonal) (M01)
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BACKGROUND
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
REFERENCES
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086. MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate. Jagom脌gi T, et al. Eur J Oral Sci, 2010 Jun. PMID 20572854. Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: association of DNA breaks with specific DNA motifs at PML and RARA loci. Hasan SK, et al. Genes Chromosomes Cancer, 2010 Aug. PMID 20544846. A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor. le Maire A, et al. Nat Struct Mol Biol, 2010 Jul. PMID 20543827.
