|Application ||WB, E|
|Other Accession||NP_000972, 6143, 19921 (mouse), 81767 (rat)|
|Predicted||Mouse, Rat, Dog|
|Calculated MW||23466 Da|
|Other Names||60S ribosomal protein L19, RPL19|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Ribosomal Protein L19 / RPL19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Identification of ribosomal protein L19 as a novel tumor antigen recognized by autologous cytotoxic T lymphocytes in lung adenocarcinoma. Kuroda K, et al. Cancer Sci, 2010 Jan. PMID 19799608.
The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer. Wagner K, et al. Clin Cancer Res, 2008 Aug 1. PMID 18676770.
Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. Lederer CW, et al. BMC Genomics, 2007 Jan 23. PMID 17244347.
Ribosomal protein l19 is a prognostic marker for human prostate cancer. Bee A, et al. Clin Cancer Res, 2006 Apr 1. PMID 16609016.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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