|Application ||WB, E|
|Other Accession||NP_064535, 56681, 20224 (mouse), 361842 (rat)|
|Calculated MW||22367 Da|
|Other Names||GTP-binding protein SAR1a, COPII-associated small GTPase, SAR1A, SAR1, SARA, SARA1|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-SAR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||SAR1, SARA, SARA1|
|Function||Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).|
|Cellular Location||Endoplasmic reticulum. Golgi apparatus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.
Sar1 assembly regulates membrane constriction and ER export. Long KR, et al. J Cell Biol, 2010 Jul 12. PMID 20624903.
Sar1-dependent trafficking of the human calcium receptor to the cell surface. Zhuang X, et al. Biochem Biophys Res Commun, 2010 Jun 11. PMID 20457124.
Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism. Taneja TK, et al. Hum Mol Genet, 2009 Jul 1. PMID 19357197.
Intracellular trafficking and assembly of specific Kir3 channel/G protein complexes. Robitaille M, et al. Cell Signal, 2009 Apr. PMID 19135528.
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