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Goat Anti-SLC16A7 / MCT2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-SLC16A7 / MCT2 Antibody AF1997a
    AF1997a (1 µg/ml) staining of A549 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60669
Other Accession NP_004722, 9194
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52200 Da
Additional Information
Gene ID 9194
Other Names Monocarboxylate transporter 2, MCT 2, Solute carrier family 16 member 7, SLC16A7, MCT2
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-SLC16A7 / MCT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC16A7
Synonyms MCT2
Function Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
Research Areas
Citations (0)

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Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44. Pinheiro C, et al. J Biomed Biotechnol, 2010. PMID 20454640.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Monocarboxylate transport in human corneal epithelium and cell lines. Vellonen KS, et al. Eur J Pharm Sci, 2010 Feb 19. PMID 20035863.
Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes. P茅rez de Heredia F, et al. Pflugers Arch, 2010 Feb. PMID 19876643.
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. Wheeler HE, et al. PLoS Genet, 2009 Oct. PMID 19834535.

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$ 325.00
Cat# AF1997a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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