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Goat Anti-STAP2 / BKS Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-STAP2 / BKS Antibody AF2039a
    AF2039a (0.03 µg/ml) staining of human heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-STAP2 / BKS Antibody AF2039a
    AF2039a (3.8 µg/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UGK3
Other Accession NP_001013863, 55620
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 44894 Da
Additional Information
Gene ID 55620
Other Names Signal-transducing adaptor protein 2, STAP-2, Breast tumor kinase substrate, BRK substrate, STAP2, BKS
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-STAP2 / BKS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAP2
Synonyms BKS
Function Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
Cellular Location Cytoplasm.
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.


An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.
Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. Sekine Y, et al. J Immunol, 2009 Dec 15. PMID 19933863.
The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl. Sekine Y, et al. Biochem Biophys Res Commun, 2009 Jun 26. PMID 19401194.
STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation. Ikeda O, et al. Biochem Biophys Res Commun, 2009 Jun 19. PMID 19393627.
STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1. Ikeda O, et al. Mol Cell Biol, 2008 Aug. PMID 18573890.

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$ 325.00
Cat# AF2039a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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