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Goat Anti-Swiprosin 1 / EFHD2 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-Swiprosin 1 / EFHD2 Antibody AF2054a
    AF2054a (0.1 µg/ml) staining of human lymph node lysate. Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - Goat Anti-Swiprosin 1 / EFHD2 Antibody AF2054a
    B6552 (2 µg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96C19
Other Accession NP_077305, 79180, 27984 (mouse)
Reactivity Human, Mouse
Predicted Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 26697 Da
Additional Information
Gene ID 79180
Other Names EF-hand domain-containing protein D2, Swiprosin-1, EFHD2, SWS1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Swiprosin 1 / EFHD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFHD2
Synonyms SWS1
Function May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Cellular Location Membrane raft. Note=In a mouse immature B-cell line WEHI-231.
Tissue Location Found in lymphocytes; preferentially expressed in CD8+ cells.
Research Areas
Citations (0)

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Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.
Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway. Thylur RP, et al. J Cell Biochem, 2009 Oct 15. PMID 19693767.
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. Martins-de-Souza D, et al. Eur Arch Psychiatry Clin Neurosci, 2009 Apr. PMID 19165527.
The novel adaptor protein Swiprosin-1 enhances BCR signals and contributes to BCR-induced apoptosis. Avramidou A, et al. Cell Death Differ, 2007 Nov. PMID 17673920.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.

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$ 325.00
Cat# AF2054a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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