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Goat Anti-TRABID / ZRANB1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-TRABID / ZRANB1 Antibody AF2104a
    AF2104a (0.1 µg/ml) staining of Human Cerebellum ysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UGI0
Other Accession NP_060050, 54764, 360216 (mouse)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 80967 Da
Additional Information
Gene ID 54764
Other Names Ubiquitin thioesterase ZRANB1,, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-TRABID / ZRANB1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TRABID
Function Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'- linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Cellular Location Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Tran H, et al. Genes Dev, 2008 Feb 15. PMID 18281465.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Isolation and characterization of two novel A20-like proteins. Evans PC, et al. Biochem J, 2001 Aug 1. PMID 11463333.

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$ 325.00
Cat# AF2104a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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