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Goat Anti-XPNPEP1 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-XPNPEP1 Antibody AF2165a
    AF2165a (0.3 µg/ml) staining of Human Pancreas lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQW7
Other Accession NP_001161076, 7511, 170750 (mouse), 170751 (rat)
Reactivity Human, Mouse, Rat
Predicted Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 69918 Da
Additional Information
Gene ID 7511
Other Names Xaa-Pro aminopeptidase 1,, Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, sAmp, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1, soluble, XPNPEP1 {ECO:0000312|EMBL:AAH05126.1}
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-XPNPEP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XPNPEP1 {ECO:0000312|EMBL:AAH05126.1}
Function Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
Cellular Location Cytoplasm.
Tissue Location Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.
Research Areas
Citations (0)

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This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.


Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. Garcia-Barcel贸 MM, et al. Hum Mol Genet, 2010 Jul 15. PMID 20460270.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill. Cilia La Corte AL, et al. J Renin Angiotensin Aldosterone Syst, 2008 Dec. PMID 19126663.
Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II)-dependent dimeric enzyme with a novel three-domain subunit. Li X, et al. J Biol Chem, 2008 Aug 15. PMID 18515364.
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451.

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$ 325.00
Cat# AF2165a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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