|Application ||WB, E|
|Other Accession||NP_085144, 80830|
|Calculated MW||38128 Da|
|Other Names||Apolipoprotein L6, Apolipoprotein L-VI, ApoL-VI, APOL6|
|Format||0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-APOL6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.|
|Tissue Location||Widely expressed; highly expressed in the uterus, fetal brain and spinal cord, also detected in heart, liver, lung, colon, spleen, thymus, prostate, placenta, adrenal gland, salivary and mammary gland|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.
The apolipoprotein L family of programmed cell death and immunity genes rapidly evolved in primates at discrete sites of host-pathogen interactions. Smith EE, et al. Genome Res, 2009 May. PMID 19299565.
RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function. Liu YL, et al. Biol Psychiatry, 2008 Nov 1. PMID 18571626.
Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells. Liu Z, et al. Mol Cancer Res, 2005 Jan. PMID 15671246.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802.
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