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Goat Anti-INCA / CARD17 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-INCA / CARD17 Antibody AF2223a
    AF2223a (0.5 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5XLA6
Other Accession NP_001007233, 440068
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 11868 Da
Additional Information
Gene ID 440068
Other Names Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Inhibitory caspase recruitment domain protein, CARD17, INCA
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-INCA / CARD17 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CARD17
Synonyms INCA
Function Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Cellular Location Cytoplasm.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. Lamkanfi M, et al. J Biol Chem, 2004 Dec 10. PMID 15383541.

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$ 325.00
Cat# AF2223a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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