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Goat Anti-MAPRE3 Antibody

Peptide-affinity purified goat antibody

  • WB - Goat Anti-MAPRE3 Antibody AF2231a
    AF2231a (0.1 µg/ml) staining of Human Brain (Amygdala) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UPY8
Other Accession NP_036458, 22924, 100732 (mouse)
Reactivity Human, Mouse
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 31982 Da
Additional Information
Gene ID 22924
Other Names Microtubule-associated protein RP/EB family member 3, EB1 protein family member 3, EBF3, End-binding protein 3, EB3, RP3, MAPRE3
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-MAPRE3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
Cellular Location Cytoplasm, cytoskeleton Note=Associated with the microtubule network. Detected at the plus end of microtubules
Tissue Location Predominantly expressed in brain and muscle.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.


Molecular insights into mammalian end-binding protein heterodimerization. De Groot CO, et al. J Biol Chem, 2010 Feb 19. PMID 20008324.
Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases. Ban R, et al. J Biol Chem, 2009 Oct 9. PMID 19696028.
Mammalian end binding proteins control persistent microtubule growth. Komarova Y, et al. J Cell Biol, 2009 Mar 9. PMID 19255245.
p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway. Hsieh PC, et al. Oncogene, 2007 Jul 26. PMID 17310996.
Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.

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$ 325.00
Cat# AF2231a
(40 western blots)
Availability: 7-10 days
Bulk Size
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