|Application ||IHC, E|
|Other Accession||NP_071400.1, 64061|
|Calculated MW||79435 Da|
|Other Names||Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DENTT / CDA1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CDA1, DENTT, TSPX|
|Function||Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.|
|Cellular Location||Nucleus. Cytoplasm Note=Enriched in transcriptionally active regions of chromatin in neurons.|
|Tissue Location||Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Differentially expressed nucleolar transforming growth factor-beta1 target
(DENTT) exhibits an inhibitory role on tumorigenesis. Kandalaft LE, Zudaire E, Portal-Núñez S, Cuttitta F, Jakowlew SB Carcinogenesis. 2008 Jun;29(6):1282-9 PMID: 18381359
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