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SOCS4 Antibody (C-Term)

Peptide-affinity purified goat antibody

  • IHC - SOCS4 Antibody (C-Term) AF2255a
    AF2255a (3.8 µg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXH5
Other Accession NP_543143.1, NP_955453.1, 122809
Reactivity Human
Predicted Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 50623 Da
Additional Information
Gene ID 122809
Other Names Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOCS4 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOCS4
Synonyms SOCS7
Function SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
Research Areas
Citations (0)

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Both variants represent identical protein (NP_543143.1 and NP_955453.1).


Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor
receptor signaling. Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N, Rechavi G, Yarden
Y. J Biol Chem. 2005 Feb 25;280(8):7038-48. PMID: 15590694

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$ 325.00
Cat# AF2255a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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