|Application ||IHC, E|
|Other Accession||NP_001124334.1, NP_006470, 10635|
|Calculated MW||38457 Da|
|Other Names||RAD51-associated protein 1, RAD51-interacting protein, R51A1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PIR51 / RAD51AP1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.|
|Cellular Location||Nucleus. Note=Colocalizes with RAD51 to multiple nuclear foci.|
|Tissue Location||Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognise both reported isoforms.
A novel nucleic acid-binding protein that interacts with human rad51 recombinase. Kovalenko OV, Golub EI, Bray-Ward P, Ward DC, Radding CM. Nucleic Acids Res. 1997 Dec 15;25(24):4946-53. PMID: 9396801
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.